Freeze-drying, tseem hu ua freeze-drying, yog cov txheej txheem qis-kub dehydration siv los kho cov khoom kub-rhiab. Lub tshuab tam sim no yog tus qauv kev coj ua hauv ntau lub tuam txhab tshuaj. Vim nws maj mam dries cov khoom yam tsis muaj kev puas tsuaj rau nws cov khoom lom thiab lub cev.
Ib, kev kho mob khov-drying tshuab keeb kwm
Xyoo 1906, Jacques-Arsene de Assonval tau tsim txoj kev khov-qhuav ntawm College de France hauv Paris. Tom qab ntawd, thaum Tsov Rog Ntiaj Teb Zaum II, nws tau dav siv los khaws cov ntshav. Txij thaum ntawd los, khov-drying tau dhau los ua ib qho ntawm cov txheej txheem tseem ceeb tshaj plaws rau kev khaws cia cov khoom siv hluav taws xob thiab cov khoom siv roj ntsha.
Piv txwv li, qhov zoo ntawm kev kho mob khov-drying tshuab
1, tswj cov khoom siv tshuaj thiab lub cev
Tsis zoo li cov txheej txheem ziab tshav kub, kev ziab kom qhuav siv qhov kub thiab txias thiab txheej txheem hu ua sublimation thiab desorption kom vaporize dej. Nws tsis txhob muaj cua sov ntau dhau los tiv thaiv kev ncaj ncees ntawm cov khoom, uas tsis cuam tshuam rau cov tshuaj lom neeg lossis lub cev.
2. Khaws kev ua haujlwm lom neeg
Rau kev lag luam kws tshuaj, qhov twg ntau cov khoom thiab cov qauv yog cov khoom tawg yooj yim, tsis ruaj khov, thiab kub-rhiab, cov txheej txheem khaws cia no yog qhov zoo tagnrho. Feem ntau freeze-drying kom muaj kev lom zem> 90%.
3, yooj yim rau khaws thiab thauj
Cov dej noo ntawm cov tshuaj khov-qhuav yog <3%, uas yog qhov tsim nyog rau kev khaws cia ntev thiab kev thauj mus los ntawm chav tsev kub. Tsuas yog ntxiv dej kom rov qab kho cov khoom rau nws qhov qub. Lub peev xwm los txhim kho cov khoom ruaj khov thiab ua kom lub txee lub neej ntawm cov tshuaj thiab cov tshuaj tau ua kom khov kom qhuav yog ib qho kev siv dav hauv kev lag luam kws tshuaj. Lub txee lub neej ntawm cov neeg ua haujlwm khov-qhuav tau hais tias tsawg kawg yog 5 xyoos thiab txog li 30 xyoo.
Piv txwv li, kev siv ntau yam kev kho mob khov-drying tshuab
1. Pharmaceutical hmoov
a: Txhaj tshuaj: khov-dried compound glycyrrhizin, recombinant human interferon γ, thiab lwm yam.
Stem cell, biopharmaceutical, tshuaj tshuaj;
b: Tshuaj tiv thaiv: tshuaj tiv thaiv kab mob encephalitis inactivated, intradermal txhaj tshuaj tiv thaiv BCG, mumps nyob attenuated tshuaj tiv thaiv, yellow fever nyob attenuated tshuaj tiv thaiv, thiab lwm yam.
c: Protein: immunoglobulin, human prothrombin complex, human fibrinogen, nab venom serum, scorpion venom serum, Staphylococcus A protein ntshiab cov khoom, thiab lwm yam .;
d: Tshuaj tua kab mob: khov-dried diphtheria antitoxin, khov-dried tetanus antitoxin, thiab lwm yam.;
2. Suav Cov Khoom Siv Tshuaj (tiav)
a: Nroj tsuag: Ginseng, Notoginseng, American ginseng, Dendrobium, Scutellaria skullcap, Licorice, Radix salva, Wolfberry, safflower, honeysuckle, chrysanthemum, Ganoderma lucidum, qhiav, Peony, peony, Rehmannia, Gink (Huachean), , txiv kab ntxwv tev, Tremella tremella, Hawthorn, txiv hmab txiv ntoo, Gastrodia gastrodia, Tianshan Snow Lotus, thiab lwm yam.;
b: Tsiaj txhu: muaj koob muaj npe jelly, placenta, cordyceps, seahorse, dais gall, mos lwj antler, mos lwj ntshav, musk, ejiao, heparin sodium, thiab lwm yam.;
3. Cov khoom siv raw
Biological raw khoom, tsiaj raw cov ntaub ntawv, tshuaj raw khoom, concentrated extraction tshuaj;
4. Tshawb xyuas reagent
Kev ntsuam xyuas ib puag ncig: dej zoo kuaj cov tshuaj reagents, kuaj av reagents thiab lwm yam khov-qhuav;
Diagnostic detection reagent, tshuaj ntsuam xyuas reagent, biochemical detection reagent;
5, kab mob lom, cov ntaub so ntswg lom
Piv txwv li, ua kom muaj ntau yam tsiaj thiab nroj tsuag, qhuav thiab khaws cia ntawm daim tawv nqaij, pob txha, pob txha, aorta, lub plawv valve thiab lwm yam marginal ntaub so ntswg ntawm xenogeneic los yog homologous transplantation ntawm cov tsiaj, xws li khov-qhuav;
6. Cov kab mob thiab cov kab mob algae
Xws li ntau yam kab mob, poov xab, enzymes, protozoa, micro-algae thiab lwm yam kev khaws cia ntev, xws li khov-qhuav.
7, cov khoom siv roj ntsha, tshuaj
Xws li kev khaws cia ntawm cov tshuaj tua kab mob, tshuaj tua kab mob, cov khoom siv tshuaj ntsuam xyuas thiab tshuaj tiv thaiv;
四, tshuaj khov-drying txheej txheem
Qhov tseem ceeb, cov tshuaj khov-qhuav qhuav muaj peb kauj ruam tseem ceeb: khov, ua kom qhuav, thiab ua kom qhuav, uas suav nrog:
Freezing: Cov khoom siv dej khov sai sai los tiv thaiv kev tsim cov pob zeb loj uas tuaj yeem ua rau cov phab ntsa ntawm tes ntawm cov khoom puas.
Kev ziab thawj zaug (sublimation): Qhov no yog theem ob ntawm cov txheej txheem khov-drying, uas txo qis thiab cua sov ua rau cov dej khov rau evaporate. Nyob ntawm tus qauv, cov txheej txheem no tuaj yeem siv sijhawm nyob qhov twg los ntawm ob peb teev mus rau ob peb hnub kom tiav. Thaum thawj qhov ziab kom tiav, 93-95% ntawm cov dej tau sublimed tawm.
Secondary drying (adsorption): Qhov no yog theem kawg uas qhov ntsuas kub tau nce ntxiv kom tshem tawm cov seem seem. Cov dej seem uas nyob rau hauv cov khoom matrix yog desorbed los ntawm kev ua kom kub.
Cov tshuaj khov-qhuav yog ces ntim rau hauv iav vials nrog roj hmab stoppers thiab txhuas crimped caps.
五. Cov tshuaj tsim nyog rau kev ziab kom qhuav
Piv txwv ntawm cov tshuaj khov-qhuav yog:
tshuaj tiv thaiv.
tshuaj tiv thaiv.
erythrocyte
ntshav ntshav
tshuaj hormone
kab mob
Ib tus kab mob.
enzyme
probiotics
Cov vitamins thiab minerals
Collagen peptide
electrolyte
Active tshuaj muaj
六, kws tshuaj khov tshuab ziab khaub ncaws pom zoo
Experimental freeze-dryer
Pilot freeze dryer
Biological freeze-dryer
Raws li cov kws tshaj lij ntawm cov tshuab ziab khaub ncaws khov thiab cov kev daws teeb meem, "BOTH" Instrument muaj kev paub dhau los hauv R & D thiab ntau lawm.Experimental freeze dryer, pilot freeze-dryerthiabbiological freeze-dryertsim los ntawm "OB" tuaj yeem ua tau raws li cov kev xav tau ntawm cov qauv me me, kev tsav tsheb lossis cov qauv loj, yog tias koj xav tau, thovtiv tauj peb, peb zoo siab los muab kev sab laj rau koj thiab teb cov lus nug koj muaj. Peb pab neeg yuav zoo siab los pab koj. tos ntsoov rau kev sib txuas lus thiab koom tes nrog koj! "
Post lub sij hawm: Jan-12-2024
